Searchable abstracts of presentations at key conferences in endocrinology

ea0094p231 | Neuroendocrinology and Pituitary | SFEBES2023

Analyses of the effects of adrenomedullin on the gonadotrophin-releasing hormone pulse generator and luteinising hormone pulses

Oshimo Yukina , Sato Marimo , Kondo Yuri , Hayashi Natsuho , Cui Wenhao , Nakamura Sho , Matsuyama Shuichi , Ohkura Satoshi , Magata Fumie , Matsuda Fuko

The pulse mode of gonadotrophin-releasing hormone (GnRH) release from the hypothalamus and following luteinising hormone (LH) pulses from the pituitary induce follicular development in female animals. Kisspeptin neurons in the hypothalamic arcuate nucleus (ARC) are suggested to be the GnRH pulse generator. Adrenomedullin (AM) is a secretory peptide expressed in various tissues, including the hypothalamic paraventricular nucleus, but its functions in the central regulation of r...